Pathophysiology of advanced glycation end-products in renal failure
نویسندگان
چکیده
منابع مشابه
Advanced glycation end products
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...
متن کاملRemoval of advanced glycation end products in clinical renal failure by peritoneal dialysis and haemodialysis.
AGEs (advanced glycation end products) accumulate markedly in the plasma of human subjects with renal failure. We investigated the efficiency of removal of AGEs from the circulation by PD (peritoneal dialysis) and HD (haemodialysis) therapy. Free AGEs were measured by LC-MS/MS in blood plasma before dialysis, in dialysis fluid effusate after a 2-12 h dwell time in the peritoneal cavity of PD su...
متن کاملRestriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients.
Advanced glycation endproduct (AGE) levels are elevated in renal failure patients and may contribute to the excessive cardiovascular disease in this population. Diet-derived AGE are major contributors to the total body AGE pool. It was postulated that a reduction in dietary AGE intake might impact on the high circulating AGE levels in renal failure patients. Twenty-six nondiabetic renal failure...
متن کاملAdvanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer.
BACKGROUND Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement. METHODS We examined the association between N(ε)-(carboxymethyl)lysine (CML), a prom...
متن کاملSalvia reuterana Extract Prevents Formation of Advanced Glycation End Products: An In Vitro Study
In this study, we examined the antioxidant activities of methanolic extract of three endemic species of Salvia from Iran (S. lachno...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1996
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/11.supp5.27